Showing posts with label Science. Show all posts
Showing posts with label Science. Show all posts

Wednesday 19 February 2020

SCIENTISTS CREATE ARTIFICIAL GENOME THAT CAN REPRODUCE

https://drive.google.com/uc?export=view&id=16gNbc-4CIpGroJsCrn4kWkOV91zIOQJz
German scientists say that for the first time ever, they’ve created a lab-grown artificial genome that can reproduce itself like a natural one.

It’s not quite one of those replicants from “Blade Runner,” but it’s a step toward the holy grail of synthetic biology: fully artificial organisms that can survive and reproduce like the real thing.
In a paper published in the journal Nature Communications this week, researchers from the Max Planck Institute of Biochemistry describe how they assembled genomes made up of blueprints for proteins — and demonstrated that it was capable of replicating 116 kilobytes worth of its own RNA and DNA.

Next up, according to a press release, the team plans to build an “enveloped system” that can reproduce like this last one — but also consume nutrition and dispose of waste, like a living cell.

READ MORE: Reproductive genome from the laboratory [Max Planck Society]


Wednesday 22 January 2020

SCIENTISTS DISCOVER IMMUNE CELL THAT KILLS MOST CANCERS

A newly discovered immune cell could lead to the creation of a universal oncology treatment — a system that would work for all cancers, in all people.https://drive.google.com/uc?export=view&id=1i1bAOOH3r8oVOqKKXVae4xWI-PTr13Wo

The treatment leverages T-cells, a type of white blood cell that helps our bodies’ immune systems by scanning for and killing abnormal cells. For background, scientists have recently started harnessing that ability in the fight against cancer through CAR-T, which involves removing T-cells from a patient’s blood and genetically engineering them to seek out and destroy cancer cells.

While promising, CAR-T has limitations. It’s patient-specific, works against only a small number of cancers, and isn’t effective against solid tumors, which comprise the majority of cancers.

On Monday, researchers from Cardiff University published a new study in the journal Nature Immunology detailing their discovery of a T-Cell equipped with a new type of T-cell receptor (TCR) that recognizes a molecule called MR1.

This molecule appears on the surface of many types of cancer cells as well as healthy cells, but T-cells equipped with this TCR know to kill only cancer cells.

And not just the kind linked to a single type of cancer, either. When the Cardiff researchers equipped T-cells in lab tests with this new TCR, the cells killed lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells — all while ignoring healthy cells.

In another lab test, the team modified the T-cells of melanoma patients to express the newly discovered TCR and found that the cells could then target and destroy both that patient’s own cancer cells and the cancer cells of other patients.

The team has yet to test the modified T-cells in actual cancer patients, but when tested in mice injected with human cancers, the cells recognized the MR1 molecule and exhibited “encouraging” cancer-killing abilities, according to a Cardiff press release.

The Cardiff scientists now plan to conduct additional tests. If those goes as hoped, the treatment could be ready for patients within a few years, researcher Andrew Sewell said in the press release.

“Cancer-targeting via MR1-restricted T-cells is an exciting new frontier,” he added. “It raises the prospect of a ‘one-size-fits-all’ cancer treatment; a single type of T-cell that could be capable of destroying many different types of cancers across the population. Previously nobody believed this could be possible.”


Thursday 30 May 2019

String Theory assumes we live in a Universe with at least 10 dimensions!

The first dimension  is length, a good description of a one-dimensional object is a straight line.

Second dimension, the y-axis (or height), and you get an object that becomes a 2-dimensional shape (like a square).

The third dimension involves depth (the z-axis), and gives all objects a sense of area and a cross-section. The perfect example of this is a cube.

Fourth dimension, Scientists believe that the fourth dimension is time, which governs the properties of all known matter at any given point.

Fifth dimension, we would see a world slightly different from our own that would give us a means of measuring the similarity and differences between our world and other possible ones.

In the sixth, we would see a plane of possible worlds, where we could compare and position all the possible universes that start with the same initial conditions as this one (i.e. the Big Bang). 

In the seventh dimension, you have access to the possible worlds that start with different initial conditions. Whereas in the fifth and sixth, the initial conditions were the same and subsequent actions were different, here, everything is different from the very beginning of time. 

The eighth dimension again gives us a plane of such possible universe histories, each of which begins with different initial conditions and branches out infinitely (hence why they are called infinities).

In the ninth dimension, we can compare all the possible universe histories, starting with all the different possible laws of physics and initial conditions. 

In the tenth and final dimension, we arrive at the point in which everything possible and imaginable is covered. Beyond this, nothing can be imagined by us lowly mortals, which makes it the natural limitation of what we can conceive in terms of dimensions.


Sunday 25 June 2017

10 Science Mysteries Waiting to Be Solved


The world of science creates mysteries as fast as it solves them — and sometimes even faster. Here are just a few of those mysteries that are waiting to be solved.

1. The impossible EM drive…works? Since first hearing rumors about NASA’s physics-breaking propulsion system late last year, a paper describing their device has passed peer-review, and China claims to be testing their own version in space right now.

And yet, no one can explain how this fuel-less drive is able to violate Newton’s Third Law: everything must have an equal and opposite reaction. If we learn anything this year or next, let’s hope we can get to the bottom of this confounding machine.

2. Humpback whales have been forming mysterious “super-groups,” and we still don’t know why. Back in March, never-before-seen groups of up to 200 whales were appearing off the coast of South Africa, which is weird, because seven is usually the upper limit for these solitary animals.

The behavior could be due to changes in prey availability, or because the species has been making a surprising comeback in recent years, but the jury’s still out on this one.

3. Astronomers have found evidence of a huge ninth planet on the edge of our Solar System — but we still can’t find it, even after NASA recruited thousands of people to search for clues.

But earlier this year, we finally got an official candidate for the mysterious presence, so hopefully we don’t have to wait too much longer to discover what’s truly out there.

4. Archaeologists made a stunning discovery inside Egypt’s Great Pyramid of Giza — evidence of a strange void behind the pyramid’s north face, and an unknown cavity high up in its northeastern edge.

It’s suspected that these could represent secret chambers that have eluded researchers and looters alike for thousands of years, and archaeologists are now hoping to non-invasively scan the insides of the giant tomb to figure it out.

5. Can we please figure out the nonsense that is the Tully Monster? This ancient sea creature that’s so messed up, scientists can’t stop arguing over it.

The 300-million-year-old creature had fins like a cuttlefish, eyestalks like a crab, and a rather intimidating “jaw-on-stick,” and this jumble of body parts has seen it compared to everything from molluscs, arthropods, and worms, to more complex vertebrates like lampreys.

6. We still don’t know what’s causing fast radio bursts — arguably the weirdest phenomena in the known Universe. They’re some of the most explosive signals ever detected in space, but they’re so confounding, some scientists have even resorted to “Aliens?”

But with the exact location for one of these signals being finally pinned down last month, we might be on the brink of figuring out what’s causing them.

7. Three separate experiments have found signs of a phenomenon that goes beyond the standard model of physics, and together they’ve hit a certainty level of 4 standard deviations, indicating a 99.95 percent chance this isn’t a mistake.

If this result can be supported by further experiments, it would have profound implications for our understanding of particle physics, and force scientists to draw up a whole new branch of physics to explain it.

8. The “Alien Megastructure” star that just won’t quit. Located 1,500 light-years away, KIC 8462852 (or Tabby’s star), has been experiencing unprecedented dips in brightness — while most stars experience periodic dimming of about 1 percent, this star has clocked dips of a whopping 22 percent.

Tabby’s star is so weird, one astronomer famously suggested aliens could be involved. With the latest bout of strange light patterns giving researchers more data to work with, let’s hope they can finally figure this one out.

6. We still don’t know what’s causing fast radio bursts — arguably the weirdest phenomena in the known Universe. They’re some of the most explosive signals ever detected in space, but they’re so confounding, some scientists have even resorted to “Aliens?”

But with the exact location for one of these signals being finally pinned down last month, we might be on the brink of figuring out what’s causing them.

7. Three separate experiments have found signs of a phenomenon that goes beyond the standard model of physics, and together they’ve hit a certainty level of 4 standard deviations, indicating a 99.95 percent chance this isn’t a mistake.

If this result can be supported by further experiments, it would have profound implications for our understanding of particle physics, and force scientists to draw up a whole new branch of physics to explain it.

8. The “Alien Megastructure” star that just won’t quit. Located 1,500 light-years away, KIC 8462852 (or Tabby’s star), has been experiencing unprecedented dips in brightness — while most stars experience periodic dimming of about 1 percent, this star has clocked dips of a whopping 22 percent.

Tabby’s star is so weird, one astronomer famously suggested aliens could be involved. With the latest bout of strange light patterns giving researchers more data to work with, let’s hope they can finally figure this one out.

Sunday 26 March 2017

Secret of Our Life

The true secret to life does not lie within your DNA, but rather within the mechanisms of your cell membrane.
Each cell membrane has receptors that pick up various environmental signals, and this mechanism controls the "reading" of the genes inside your cells. Your cells can choose to read or not read the genetic blueprint depending on the signals being received from the environment. So having a "cancer program" in your DNA does not automatically mean you're destined to get cancer. Far from it. This genetic information does not ever have to be expressed...
What this all means is that you are not controlled by your genetic makeup. Instead, your genetic readout (which genes are turned "on" and which are turned "off") is primarily determined by your thoughts, attitudes, and perceptions!
The major problem with believing the myth that your genes control your life is that you become a victim of your heredity. Since you can't change your genes, it essentially means that your life is predetermined, and therefore you have very little control over your health. With any luck, modern medicine will find the gene responsible and be able to alter it, or devise some other form of drug to modify your body's chemistry, but aside from that, you're out of luck… The new science, however, reveals that your perceptions control your biology, and this places you in the driver's seat, because if you can change your perceptions, you can shape and direct your own genetic readout.